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Sudden Shake-Up at the Justice Department

Attorney General Pam Bondi is sworn in ahead of testifying before a House Judiciary Committee hearing on oversight of the Justice Department, on Capitol Hill. In a surprising move that has sent shockwaves through Washington, former President Donald Trump has dismissed Pam Bondi from her role as U.S. Attorney General. The decision, announced abruptly, has sparked widespread speculation about the motivations behind the firing and its potential political implications. Bondi, who had been a loyal ally of Trump, was appointed amid promises to reinforce the administration’s law-and-order agenda. Her tenure, however, was marked by both staunch support from Trump’s base and criticism from opponents who questioned her independence. Sources close to the situation suggest that internal disagreements and strategic differences may have played a role in the decision. Others point to broader political calculations as Trump continues to reshape his inner circle. The sudden leadership change raises que...
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Alzheimer’s vaccines get a boost from new drug approval

 

After decades of disappointment and controversy, the field of Alzheimer’s disease research has finally seen a breakthrough with the approval of the first drug that targets the underlying pathology of the condition. 

Aducanumab, a monoclonal antibody that clears amyloid plaques from the brain, was granted accelerated approval by the US Food and Drug Administration in June 2021, despite mixed results from clinical trials and objections from some experts. 

The drug’s approval has rekindled interest in other therapeutic approaches that aim to prevent or slow down the progression of Alzheimer’s, such as vaccines that stimulate the immune system to attack amyloid or tau, another protein that accumulates in the brains of people with the disease. 

Several vaccine candidates are currently in various stages of development and testing, and some researchers are optimistic that they could offer a more effective and convenient way to treat Alzheimer’s than infusions of antibodies.


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