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Wall St Futures Slip as Geopolitical Uncertainty and Mixed Earnings Weigh on Sentiment

Wall Street futures slipped early Thursday as investors grew cautious in the absence of clear signals on the U.S.–Iran war, while a wave of mixed earnings added to the uncertainty. Iran’s seizure of two ships in the Strait of Hormuz and its demand that the U.S. lift its naval blockade have heightened geopolitical tensions, even after President Donald Trump extended the ceasefire indefinitely. The standoff continues to keep oil prices above $100 per barrel , raising concerns about a potential inflation flare‑up.  Economists warn that even if the conflict eases, the global economy may take time to normalize after one of the largest oil supply disruptions in decades.  As of early morning trading, Dow E‑minis were down 0.73%, S&P 500 E‑minis slipped 0.50%, and Nasdaq 100 E‑minis fell 0.48% , reflecting a broader pullback in risk appetite.  Earnings added another layer of volatility. Tesla shares fell after the company boosted its annual spending plan to more than $25...
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Alzheimer’s vaccines get a boost from new drug approval

 

After decades of disappointment and controversy, the field of Alzheimer’s disease research has finally seen a breakthrough with the approval of the first drug that targets the underlying pathology of the condition. 

Aducanumab, a monoclonal antibody that clears amyloid plaques from the brain, was granted accelerated approval by the US Food and Drug Administration in June 2021, despite mixed results from clinical trials and objections from some experts. 

The drug’s approval has rekindled interest in other therapeutic approaches that aim to prevent or slow down the progression of Alzheimer’s, such as vaccines that stimulate the immune system to attack amyloid or tau, another protein that accumulates in the brains of people with the disease. 

Several vaccine candidates are currently in various stages of development and testing, and some researchers are optimistic that they could offer a more effective and convenient way to treat Alzheimer’s than infusions of antibodies.


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