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U.S. Officials Say Iran’s New Supreme Leader Gravely Wounded Amid Escalating Conflict

Protesters hold posters of Iran's late Supreme Leader Ayatollah Ali Khamenei and his son, Iran's new Supreme Leader Mojtaba Khamenei, during a protest marking al-Quds Day (Jerusalem Day), after Friday prayers at Fatih Mosque in Istanbul. U.S. Defense Secretary Pete Hegseth has confirmed that Iran’s newly appointed Supreme Leader, Mojtaba Khamenei , was seriously wounded and likely disfigured during the opening phase of U.S. and Israeli military strikes. Speaking at a Pentagon briefing, Hegseth described Iran’s leadership as “desperate and hiding,” asserting that Khamenei has gone underground following injuries sustained in the attacks.  Reports from multiple outlets indicate that Khamenei has not appeared publicly since the conflict began, fueling speculation about the severity of his condition. Some accounts suggest he may have suffered catastrophic injuries, including the loss of a limb and a possible coma, after an airstrike that also killed members of his family.  U.S....
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Alzheimer’s vaccines get a boost from new drug approval

 

After decades of disappointment and controversy, the field of Alzheimer’s disease research has finally seen a breakthrough with the approval of the first drug that targets the underlying pathology of the condition. 

Aducanumab, a monoclonal antibody that clears amyloid plaques from the brain, was granted accelerated approval by the US Food and Drug Administration in June 2021, despite mixed results from clinical trials and objections from some experts. 

The drug’s approval has rekindled interest in other therapeutic approaches that aim to prevent or slow down the progression of Alzheimer’s, such as vaccines that stimulate the immune system to attack amyloid or tau, another protein that accumulates in the brains of people with the disease. 

Several vaccine candidates are currently in various stages of development and testing, and some researchers are optimistic that they could offer a more effective and convenient way to treat Alzheimer’s than infusions of antibodies.


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