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Winter Storm Near Miss: Southern Ontario Could Still See Heavy Snow

  A major winter storm developing across the central United States is expected to track close enough to southern Ontario this weekend to bring the risk of significant snowfall. While the core of the system is projected to remain south of the border, its northern edge may still sweep across regions from Windsor to the Greater Toronto Area. Forecasters say the exact path remains uncertain, but current projections suggest that areas along and south of Highway 401 could see notable accumulations if the storm shifts even slightly north. Some models indicate the potential for 10–20 centimetres of snow, with locally higher amounts possible if lake‑enhanced bands develop. The storm threat comes as southern Ontario braces for a surge of bitter cold. Wind chills dipping into the minus twenties may precede the system, creating conditions that could intensify snowfall rates and make travel more difficult. Meteorologists continue to monitor the storm’s trajectory closely. Residents are enco...

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Alzheimer’s vaccines get a boost from new drug approval

 

After decades of disappointment and controversy, the field of Alzheimer’s disease research has finally seen a breakthrough with the approval of the first drug that targets the underlying pathology of the condition. 

Aducanumab, a monoclonal antibody that clears amyloid plaques from the brain, was granted accelerated approval by the US Food and Drug Administration in June 2021, despite mixed results from clinical trials and objections from some experts. 

The drug’s approval has rekindled interest in other therapeutic approaches that aim to prevent or slow down the progression of Alzheimer’s, such as vaccines that stimulate the immune system to attack amyloid or tau, another protein that accumulates in the brains of people with the disease. 

Several vaccine candidates are currently in various stages of development and testing, and some researchers are optimistic that they could offer a more effective and convenient way to treat Alzheimer’s than infusions of antibodies.


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