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From Slopes to Shadows: The Rise and Fall of Ryan Wedding

Ryan James Wedding’s life reads like a cautionary tale of talent, ambition, and a descent into infamy. Once celebrated as a Canadian Olympian, he is now branded by U.S. authorities as one of the world’s most violent drug traffickers. Here’s a timeline tracing his dramatic transformation: Early Promise (2002) Wedding represented Canada at the Salt Lake City Winter Olympics , competing in the men’s parallel giant slalom snowboarding event. Seen as a rising star, his athletic career was short-lived, with little public spotlight after the Games. First Legal Troubles (2000s–2010s) Reports suggest Wedding became entangled in criminal networks during the years following his Olympic appearance. By the early 2010s, he was linked to drug trafficking operations, allegedly building ties with the Sinaloa cartel . Alleged Cartel Leadership (2015–2020) In 2015 , Wedding fled authorities, beginning his life as a fugitive. U.S. investigators accuse him of running a billion-dollar cocaine...
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Alzheimer’s vaccines get a boost from new drug approval

 

After decades of disappointment and controversy, the field of Alzheimer’s disease research has finally seen a breakthrough with the approval of the first drug that targets the underlying pathology of the condition. 

Aducanumab, a monoclonal antibody that clears amyloid plaques from the brain, was granted accelerated approval by the US Food and Drug Administration in June 2021, despite mixed results from clinical trials and objections from some experts. 

The drug’s approval has rekindled interest in other therapeutic approaches that aim to prevent or slow down the progression of Alzheimer’s, such as vaccines that stimulate the immune system to attack amyloid or tau, another protein that accumulates in the brains of people with the disease. 

Several vaccine candidates are currently in various stages of development and testing, and some researchers are optimistic that they could offer a more effective and convenient way to treat Alzheimer’s than infusions of antibodies.


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